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Title: | Passerini multicomponent reactions |
Authors: | Marqués-López, Eugenia ![]() |
Keywords: | Multicomponent reaction Microwave Solvent-free PEG Ionic liquids Aqueous media Passerini reaction Macrocycles Peptidomimetic α-hydroxycarboxamide |
Issue Date: | 2015 |
Publisher: | John Wiley & Sons |
Citation: | Multicomponent Reactions: Concepts and Applications for Design and Synthesis (Cap.8): 283-305 (2015) |
Abstract: | The Passerini reaction is a pivotal isocyanide-based multicomponent reaction together with Ugi reaction and it provides easy access to α-acyloxy carboxamides in a one-pot synthesis involving an aldehydes, isonitriles, and a carboxylic acid. In this chapter, some pivotal examples will be remarked covering different aspects of this reaction. Interesting targets synthesized following this MCR as a key synthetic step will be also disclosed. Additionally, some interesting environmentally-benign protocols have been remarked. |
URI: | http://hdl.handle.net/10261/156415 |
DOI: | http://dx.doi.org/10.1002/9781118863992.ch8 |
Identifiers: | doi: 10.1002/9781118863992.ch8 isbn: 9781118016008 |
Appears in Collections: | (ISQCH) Libros y partes de libros |
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