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Title

Passerini multicomponent reactions

AuthorsMarqués-López, Eugenia ; Herrera, Raquel P.
KeywordsMulticomponent reaction
Microwave
Solvent-free
PEG
Ionic liquids
Aqueous media
Passerini reaction
Macrocycles
Peptidomimetic
α-hydroxycarboxamide
Issue Date2015
PublisherJohn Wiley & Sons
CitationMulticomponent Reactions: Concepts and Applications for Design and Synthesis (Cap.8): 283-305 (2015)
AbstractThe Passerini reaction is a pivotal isocyanide-based multicomponent reaction together with Ugi reaction and it provides easy access to α-acyloxy carboxamides in a one-pot synthesis involving an aldehydes, isonitriles, and a carboxylic acid. In this chapter, some pivotal examples will be remarked covering different aspects of this reaction. Interesting targets synthesized following this MCR as a key synthetic step will be also disclosed. Additionally, some interesting environmentally-benign protocols have been remarked.
URIhttp://hdl.handle.net/10261/156415
DOIhttp://dx.doi.org/10.1002/9781118863992.ch8
Identifiersdoi: 10.1002/9781118863992.ch8
isbn: 9781118016008
Appears in Collections:(ISQCH) Libros y partes de libros
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