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Passerini multicomponent reactions

AutorMarqués-López, Eugenia ; Herrera, Raquel P.
Palabras claveMulticomponent reaction
Microwave
Solvent-free
PEG
Ionic liquids
Aqueous media
Passerini reaction
Macrocycles
Peptidomimetic
α-hydroxycarboxamide
Fecha de publicación2015
EditorJohn Wiley & Sons
CitaciónMulticomponent Reactions: Concepts and Applications for Design and Synthesis (Cap.8): 283-305 (2015)
ResumenThe Passerini reaction is a pivotal isocyanide-based multicomponent reaction together with Ugi reaction and it provides easy access to α-acyloxy carboxamides in a one-pot synthesis involving an aldehydes, isonitriles, and a carboxylic acid. In this chapter, some pivotal examples will be remarked covering different aspects of this reaction. Interesting targets synthesized following this MCR as a key synthetic step will be also disclosed. Additionally, some interesting environmentally-benign protocols have been remarked.
URIhttp://hdl.handle.net/10261/156415
DOI10.1002/9781118863992.ch8
Identificadoresdoi: 10.1002/9781118863992.ch8
isbn: 9781118016008
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