English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/156412
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Multicomponent reactions in the synthesis of target molecules

AutorRadtke, Lea; Marqués-López, Eugenia ; Herrera, Raquel P.
Palabras claveDihydropyrimidine
Spiro compound
Fused polyheterocycle
Asymmetric catalysis
Indole
Heterocycle
Target molecule
Natural product
Multicomponent reaction
Drug discovery
Fecha de publicación2015
EditorJohn Wiley & Sons
CitaciónMulticomponent Reactions: Concepts and Applications for Design and Synthesis (Cap.6): 198-246 (2015)
ResumenMulticomponent reactions are a powerful tool in the synthesis of complex target molecules because multiple bonds are effectively built up in one step from relatively simple building blocks. They introduce molecular diversity in only one step and do so in a highly efficient and convergent manner. Heterocycles are structural motifs that are often found in bioactive molecules or drugs, therefore the high yielding and fewer steps synthesis of these compounds is of great interest for Medicinal Chemistry. Here, we will discuss some multicomponent strategies to synthesize heterocycles like indoles, pyrroles, spiro-type polyheterocycles, fused polyheterocycles, dihydropyrimidines, thiazines, as well as amino acids.
URIhttp://hdl.handle.net/10261/156412
DOI10.1002/9781118863992.ch6
Identificadoresdoi: 10.1002/9781118863992.ch6
isbn: 9781118016008
Aparece en las colecciones: (ISQCH) Libros y partes de libros
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
accesoRestringido.pdf15,38 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.