English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/155677
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Recent advances in the preparation of enantiomerically pure hydroxylamines from nitrones

AutorMatute, Rosa; García-Viñuales, Sara; Hayes, Heather; Ghirardello, Mattia ; Darù, Andrea; Tejero, Tomás ; Delso, J. Ignacio; Merino, Pedro
Palabras claveReductive coupling
Mannich
Organometallics
Nitrones
Hydroxylamines
Fecha de publicación2016
EditorBentham Science Publishers
CitaciónCurrent Organic Synthesis 13(5): 669-686 (2016)
ResumenThis review covers the recent advances in the synthesis of enantiomerically pure hydroxylamine’s employing nitrones as starting materials. Nucleophilic additions of organometallic reagents to nitrones are the most common way for introducing a hydroxyamino group into carbon skeletons with the concomitant formation of a new carbon-carbon bond. Addition of nucleophiles derived from enolates, cyanide or fluorinated derivatives allows the preparation of complex structures. Radical additions and, in particular samarium diiodidemediated reductive coupling of nitrones with carbonyl compounds and α,β-unsaturated esters have also been considered. All these approaches provide efficient methods of preparation of enantiomerically pure hydroxylamine’s that are valuable synthetic intermediates.
Versión del editorhttps://doi.org/10.2174/1570179412666150914200035
URIhttp://hdl.handle.net/10261/155677
DOI10.2174/1570179412666150914200035
Identificadoresdoi: 10.2174/1570179412666150914200035
issn: 1570-1794
e-issn: 1875-6271
Aparece en las colecciones: (ISQCH) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
enantiomerically pure.pdf638,96 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.