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http://hdl.handle.net/10261/153779
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Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Fuentes, Gloria | es_ES |
dc.contributor.author | Oyarzabal, Julen | es_ES |
dc.contributor.author | Rojas Mendoza, Ana M. | es_ES |
dc.date.accessioned | 2017-08-02T09:08:04Z | - |
dc.date.available | 2017-08-02T09:08:04Z | - |
dc.date.issued | 2009-05 | - |
dc.identifier.citation | Current Opinion in Drug Discovery and Development 12(3): 358-366 (2009) | es_ES |
dc.identifier.issn | 1367-6733 | - |
dc.identifier.uri | http://hdl.handle.net/10261/153779 | - |
dc.description.abstract | Proteins rarely act alone. With the development of experimental technologies, researchers have started to map the interactions of proteins in different organisms. The data gathered constitute potential frameworks for system-based drug discovery. The possibility of targeting protein-protein interactions with specific drugs raises expectations of huge impact in the therapeutics field, despite the large quantity of research still necessary to delineate the complete interactome of a single cell. This review summarizes some concepts relating to protein-protein interfaces in relation to drug discovery, and discusses studies aiming to develop protein-protein interaction modulators through the combination of in silico and in vitro screening experiments. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Thomson Reuters | es_ES |
dc.rights | closedAccess | es_ES |
dc.title | Databases of protein-protein interactions and their use in drug discovery | es_ES |
dc.type | artículo | es_ES |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.identifier.e-issn | 2040-3437 | - |
dc.relation.csic | No | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
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