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dc.contributor.authorMedrano Domínguez, Maytees_ES
dc.contributor.authorBarbado, Victoriaes_ES
dc.contributor.authorCampillo, Nuria E.es_ES
dc.contributor.authorHidalgo Casado, Franciscoes_ES
dc.contributor.authorCaballero-Velázquez, Teresaes_ES
dc.contributor.authorÁlvarez Laderas, Isabeles_ES
dc.contributor.authorLópez, Óscares_ES
dc.contributor.authorPiruat, José I.es_ES
dc.contributor.authorPérez-Simón, José A.es_ES
dc.date.accessioned2017-07-27T11:32:27Z-
dc.date.available2017-07-27T11:32:27Z-
dc.date.issued2017-06-26-
dc.identifier.citationhaematologica 102(s2)208 (2017)es_ES
dc.identifier.issn0390-6078-
dc.identifier.urihttp://hdl.handle.net/10261/153644-
dc.description2 p. 22nd Congress of the European Hematology Association. Madrid, Spain, June 22 - 25, 2017es_ES
dc.description.abstractEndocannabinoid system is a set of ligands, receptors and endogenous enzymes which modulate a variety of physiological effects. There are two well-characterized cannabinoid receptors, CB1 (mainly expressed in Central Nervous System) and CB2 (mainly in hematopoietic cells). Here, we tested the effect of the cannabinoid WIN-55 212-2 in acute myeloid leukemia (AML) in vitro and in vivo and studied the molecular signaling pathways involved in this effect, specially the role of sphingolipids. Moreover, we synthesized a new family of twelve cannabinoids that are specific to CB2 receptor.es_ES
dc.language.isoenges_ES
dc.publisherFerrata Storti Foundationes_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rightsopenAccesses_ES
dc.titleCannabinoids derivatives modify the pattern of sphingolipids in acute myeloid leukemia cells and produce a potent anti-leukemic effectes_ES
dc.typecomunicación de congresoes_ES
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://www.haematologica.org/content/102/s2es_ES
dc.identifier.e-issn1592-8721-
dc.relation.csices_ES
oprm.item.hasRevisionno ko 0 false*
dc.type.coarhttp://purl.org/coar/resource_type/c_5794es_ES
item.openairetypecomunicación de congreso-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
Aparece en las colecciones: (CIB) Comunicaciones congresos
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