Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/152915
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Toharia, P. | - |
dc.contributor.author | Makarova, Julia | - |
dc.contributor.author | Herreras, Óscar | - |
dc.contributor.author | DeFelipe, Javier | - |
dc.contributor.author | Benavides-Piccione, Ruth | - |
dc.date.accessioned | 2017-07-14T11:25:31Z | - |
dc.date.available | 2017-07-14T11:25:31Z | - |
dc.date.issued | 2016-01-06 | - |
dc.identifier.citation | Frontiers in Neuroanatomy 9: 159 (2016) | - |
dc.identifier.issn | 1662-5129 | - |
dc.identifier.uri | http://hdl.handle.net/10261/152915 | - |
dc.description.abstract | This work presents PyramidalExplorer, a new tool to interactively explore and reveal the detailed organization of the microanatomy of pyramidal neurons with functionally related models. It consists of a set of functionalities that allow possible regional differences in the pyramidal cell architecture to be interactively discovered by combining quantitative morphological information about the structure of the cell with implemented functional models. The key contribution of this tool is the morpho-functional oriented design that allows the user to navigate within the 3D dataset, filter and perform Content-Based Retrieval operations. As a case study, we present a human pyramidal neuron with over 9000 dendritic spines in its apical and basal dendritic trees. Using PyramidalExplorer, we were able to find unexpected differential morphological attributes of dendritic spines in particular compartments of the neuron, revealing new aspects of the morpho-functional organization of the pyramidal neuron. | - |
dc.description.sponsorship | This work has been partially supported by the Spanish Ministry of Economy and Competitiveness (Grants TIN2014-57481 and BFU2013-41533R, and the Cajal Blue Brain Project C080020-09, the Spanish partner of the Blue Brain initiative from EPFL), by the European Union’s Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 604102 (Human Brain Project) and by a grant from the Alzheimer’s Association (ZEN-15-321663). RB-P was supported by the Ministerio de Economia y Competitividad (CSIC). | - |
dc.publisher | Frontiers Media | - |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/604102 | - |
dc.relation.isversionof | Publisher's version | - |
dc.rights | openAccess | - |
dc.title | PyramidalExplorer: A New Interactive Tool to Explore Morpho-Functional Relations of Human Pyramidal Neurons | - |
dc.type | artículo | - |
dc.identifier.doi | 10.3389/fnana.2015.00159 | - |
dc.description.peerreviewed | Peer reviewed | - |
dc.relation.publisherversion | http://dx.doi.org/10.3389/fnana.2015.00159 | - |
dc.date.updated | 2017-07-14T11:25:31Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | Copyright © 2016 Toharia, Robles, Fernaud-Espinosa, Makarova, Galindo, Rodriguez, Pastor, Herreras, DeFelipe and Benavides-Piccione. | - |
dc.rights.license | http://creativecommons.org/licenses/by/4.0/ | - |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | - |
dc.contributor.funder | European Commission | - |
dc.contributor.funder | Consejo Superior de Investigaciones Científicas (España) | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003339 | es_ES |
dc.identifier.pmid | 26778972 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairetype | artículo | - |
Aparece en las colecciones: | (IC) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
PyramidalExplorer.pdf | 5,56 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
6
checked on 17-abr-2024
SCOPUSTM
Citations
9
checked on 19-abr-2024
WEB OF SCIENCETM
Citations
9
checked on 28-feb-2024
Page view(s)
223
checked on 23-abr-2024
Download(s)
165
checked on 23-abr-2024