Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/152903
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Ramírez, Manuel | - |
dc.contributor.author | Velázquez, Rocío | - |
dc.contributor.author | Maqueda, Matilde | - |
dc.contributor.author | López-Piñeiro, Antonio | - |
dc.contributor.author | Ribas, Juan Carlos | - |
dc.date.accessioned | 2017-07-14T11:20:59Z | - |
dc.date.available | 2017-07-14T11:20:59Z | - |
dc.date.issued | 2015-09-15 | - |
dc.identifier.citation | Frontiers in Microbiology 6: 9983 (2015) | - |
dc.identifier.uri | http://hdl.handle.net/10261/152903 | - |
dc.description.abstract | Wine Torulaspora delbrueckii strains producing a new killer toxin (Kbarr-1) were isolated and selected for wine making. They killed all the previously known Saccharomyces cerevisiae killer strains, in addition to other non-Saccharomyces yeasts. The Kbarr-1 phenotype is encoded by a medium-size 1.7 kb dsRNA, TdV-Mbarr-1, which seems to depend on a large-size 4.6 kb dsRNA virus (TdV-LAbarr) for stable maintenance and replication. The TdV-Mbarr-1 dsRNA was sequenced by new generation sequencing techniques. Its genome structure is similar to those of S. cerevisiae killer M dsRNAs, with a 5′-end coding region followed by an internal A-rich sequence and a 3′-end non-coding region. Mbarr-1 RNA positive strand carries cis acting signals at its 5′ and 3′ termini for transcription and replication respectively, similar to those RNAs of yeast killer viruses. The ORF at the 5′ region codes for a putative preprotoxin with an N-terminal secretion signal, potential Kex2p/Kexlp processing sites, and N-glycosylation sites. No relevant sequence identity was found either between the full sequence of Mbarr-1 dsRNA and other yeast M dsRNAs, or between their respective toxin-encoded proteins. However, a relevant identity of TdV-Mbarr-1 RNA regions to the putative replication and packaging signals of most of the M-virus RNAs suggests that they are all evolutionarily related. | - |
dc.description.sponsorship | This work was funded by grants GR10088 from the Extremadura Regional Government and AGL2011-25711 from the Spanish Ministry of Education and Science. RV acknowledges support by a fellowship from the Extremadura Regional Government. | - |
dc.publisher | Frontiers Media | - |
dc.title | A new wine Torulaspora delbrueckii killer strain with broad antifungal activity and its toxin-encoding double-stranded RNA virus | - |
dc.type | artículo | - |
dc.identifier.doi | 10.3389/fmicb.2015.00983 | - |
dc.relation.publisherversion | http://dx.doi.org/10.3389/fmicb.2015.00983 | - |
dc.identifier.e-issn | 1664-302X | - |
dc.date.updated | 2017-07-14T11:20:59Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | en | - |
dc.rights.license | http://creativecommons.org/licenses/by/4.0/ | - |
dc.contributor.funder | Junta de Extremadura | - |
dc.contributor.funder | Ministerio de Educación y Ciencia (España) | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100014181 | es_ES |
dc.identifier.pmid | 26441913 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
Aparece en las colecciones: | (IBFG) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
162690.pdf | 3,77 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
28
checked on 18-mar-2024
SCOPUSTM
Citations
48
checked on 27-mar-2024
WEB OF SCIENCETM
Citations
53
checked on 24-feb-2024
Page view(s)
217
checked on 28-mar-2024
Download(s)
211
checked on 28-mar-2024