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| Título: | SeDuS: segmental duplication simulator |
Autor: | Hartasánchez Frenk, Diego CSIC; Brasó-Vives, Marina CSIC ORCID; Fuentes Díaz, Juan Manuel CSIC; Vallès-Codina, Oriol; Navarro, Arcadi CSIC ORCID | Fecha de publicación: | 1-ene-2016 | Editor: | Oxford University Press | Citación: | Bioinformatics 32(1): 148-150 (2015) | Resumen: | Summary: SeDuS is the first flexible and user-friendly forward-in-time simulator of patterns of molecular evolution within segmental duplications undergoing interlocus gene conversion and crossover. SeDuS introduces known features of interlocus gene conversion such as biased directionality and dependence on local sequence identity. Additionally, it includes aspects such as different selective pressures acting upon copy number and flexible crossover distributions. A graphical user interface allows fast fine-tuning of relevant parameters and straightforward real-time analysis of the evolution of duplicates. | Versión del editor: | https://doi.org/10.1093/bioinformatics/btv481 | URI: | http://hdl.handle.net/10261/152571 | DOI: | 10.1093/bioinformatics/btv481 | ISSN: | 1460-2059 |
| Aparece en las colecciones: | (IBE) Artículos |
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