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JSpeciesWS: a web server for prokaryotic species circumscription based on pairwise genome comparison

AuthorsRichter, Michael CSIC; Rosselló-Mora, Ramón CSIC ORCID; Glöckner, Frank Oliver; Pepiles, Jörg
Issue Date16-Nov-2016
PublisherOxford University Press
CitationBioinformatics 32: 929-931 (2016)
AbstractJSpecies Web Server (JSpeciesWS) is a user-friendly online service for in silico calculating the extent of identity between two genomes, a parameter routinely used in the process of polyphasic microbial species circumscription. The service measures the average nucleotide identity (ANI) based on BLAST+ (ANIb) and MUMmer (ANIm), as well as correlation indexes of tetra-nucleotide signatures (Tetra). In addition, it provides a Tetra Correlation Search function, which allows to rapidly compare selected genomes against a continuously updated reference database with currently about 32 000 published whole and draft genome sequences. For comparison, own genomes can be uploaded and references can be selected from the JSpeciesWS reference database. The service indicates whether two genomes share genomic identities above or below the species embracing thresholds, and serves as a fast way to allocate unknown genomes in the frame of the hitherto sequenced species. Availability and implementation: JSpeciesWS is available at Supplementary information: Supplementary data are available at Bioinformatics online.
Publisher version (URL)
Identifiersdoi: 10.1093/bioinformatics/btv681
issn: 1367-4811
Appears in Collections:(IMEDEA) Artículos

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