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dc.contributor.authorVai, Stefaniaes_ES
dc.contributor.authorMatas-Lalueza, Martaes_ES
dc.contributor.authorRamírez, Óscares_ES
dc.contributor.authorLalueza-Fox, Carleses_ES
dc.contributor.authorBarbujani, Guidoes_ES
dc.identifier.citationPLoS ONE 10(1): e0116801 (2015)es_ES
dc.descriptionVai, Stefania et al.es_ES
dc.description.abstractIn the period between 400 to 800 AD, also known as the period of the Barbarian invasions, intense migration is documented in the historical record of Europe. However, little is known about the demographic impact of these historical movements, potentially ranging from negligible to substantial. As a pilot study in a broader project on Medieval Europe, we sampled 102 specimens from 5 burial sites in Northwestern Italy, archaeologically classified as belonging to Lombards or Longobards, a Germanic people ruling over a vast section of the Italian peninsula from 568 to 774. We successfully amplified and typed the mitochondrial hypervariable region I (HVR-I) of 28 individuals. Comparisons of genetic diversity with other ancient populations and haplotype networks did not suggest that these samples are heterogeneous, and hence allowed us to jointly compare them with three isolated contemporary populations, and with a modern sample of a large city, representing a control for the effects of recent immigration. We then generated by serial coalescent simulations 16 millions of genealogies, contrasting a model of genealogical continuity with one in which the contemporary samples are genealogically independent from the medieval sample. Analyses by Approximate Bayesian Computation showed that the latter model fits the data in most cases, with one exception, Trino Vercellese, in which the evidence was compatible with persistence up to the present time of genetic features observed among this early medieval population. We conclude that it is possible, in general, to detect evidence of genealogical ties between medieval and specific modern populations. However, only seldom did mitochondrial DNA data allow us to reject with confidence either model tested, which indicates that broader analyses, based on larger assemblages of samples and genetic markers, are needed to understand in detail the effects of medieval migration.es_ES
dc.description.sponsorshipThis work was supported by the Italian Ministry for Universities and Research (MIUR), PRIN 2012 funds to DC, AA, AT and GB, FIRB funds “Futuro in Ricerca” 2008 (RBFR08U07M) and 2012 (RBFR126B8I) to AA, AO and ER; Compagnia di San Paolo, Turin to DC; the Anneliese Maier Research Award of the Alexander von Humboldt Foundation and the German Federal Ministry for Education and Research to PG; FEDER and Spanish Government grant BFU2012-34157 to CLF; European Research Council (ERC Advanced Grant No. 295733 “LanGeLin”) to GB.es_ES
dc.publisherPublic Library of Sciencees_ES
dc.relation.isversionofPublisher's versiones_ES
dc.titleGenealogical Relationships between Early Medieval and Modern Inhabitants of Piedmontes_ES
dc.description.peerreviewedPeer reviewedes_ES
dc.contributor.funderMinistero dell'Istruzione, dell'Università e della Ricercaes_ES
dc.contributor.funderCompagnia di San Paoloes_ES
dc.contributor.funderAlexander von Humboldt Foundationes_ES
dc.contributor.funderFederal Ministry of Education and Research (Germany)es_ES
dc.contributor.funderEuropean Research Counciles_ES
dc.contributor.funderEuropean Commissiones_ES
dc.contributor.funderMinisterio de Economía y Competitividad (España)es_ES
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