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iPSCs, a future tool for therapeutic intervention in mitochondrial disorders: pros and cons

AutorGalera, Teresa; Zurita Díaz, Francisco; Garesse, Rafael ; Gallardo, M. Esther
Fecha de publicación2016
EditorWiley-Liss
CitaciónJournal of Cellular Physiology 231(11): 2317-2318 (2016)
ResumenMitochondrial disorders, although individually are rare, taken together constitute a big group of diseases that share a defect in the oxidative phosphorylation system. Up to now, the development of therapies for these diseases is very slow and ineffective due in part to the lack of appropriate disease models. Therefore, there is an urgent need for the discovery of new therapeutic interventions. Regarding this, the generation of induced pluripotent stem cells (iPSCs) has opened new expectations in the regenerative medicine field. However, special cares and considerations must be taken into account previous to a replacement therapy.
Versión del editorhttps://doi.org/10.1002/jcp.25386
URIhttp://hdl.handle.net/10261/151025
DOI10.1002/jcp.25386
Identificadoresdoi: 10.1002/jcp.25386
e-issn: 1097-4652
issn: 0021-9541
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