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Título

Liquid chromatography-tandem mass spectrometry for the analysis of pharmaceutical residues in environmental samples: a review

AutorPetrovic, Mira; Hernando, María Dolores; Díaz-Cruz, M. Silvia; Barceló, Damià
Palabras claveLiquid chromatography–tandem mass spectrometry
Non-steroidal anti-inflammatory drugs
β-Blockers
Antibiotica
Lipid regulating agents
Fecha de publicación6-ene-2005
EditorElsevier
CitaciónJournal of Chromatography A 1067(1-2): 1-14 (2005)
ResumenPharmaceutical residues are environmental contaminants of recent concern and the requirements for analytical methods are mainly dictated by low concentrations found in aqueous and solid environmental samples. In the current article, a review of the liquid chromatography–tandem mass spectrometry (LC–MS/MS) based methods published so far for the determination of pharmaceuticals in the environment is presented. Pharmaceuticals included in this review are antibiotics, non-steroidal anti-inflammatory drugs, β-blockers, lipid regulating agents and psychiatric drugs. Advanced aspects of current LC–MS/MS methodology, including sample preparation and matrix effects, are discussed.
Descripción14 pages, 5 figures.-- PMID: 15844508 [PubMed].-- Printed version published Mar 4, 2005.-- Issue title: "Mass Spectrometry: Innovation and Application. Part IV".
Versión del editorhttp://dx.doi.org/10.1016/j.chroma.2004.10.110
URIhttp://hdl.handle.net/10261/15063
DOI10.1016/j.chroma.2004.10.110
ISSN0021-9673 (Print)
1873-3778 (Online)
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