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Microencapsulation structures based on protein-coated liposomes obtained through electrospraying for the stabilization and improved bioaccessibility of curcumin

AutorGómez-Mascaraque, Laura G. ; Casagrande Sipoli, Caroline; de La Torre, Lucimara Gaziola; López-Rubio, Amparo
Palabras claveElectrospraying
Liposome
Encapsulation
Curcumin
Functional food
Bioaccessibility
Fecha de publicación22-abr-2017
EditorElsevier
CitaciónFood Chemistry 233: 343-350 (2017)
ResumenNovel food-grade hybrid encapsulation structures based on the entrapment of phosphatidylcholine liposomes, within a WPC matrix through electrospraying, were developed and used as delivery vehicles for curcumin. The loading capacity and encapsulation efficiency of the proposed system was studied, and the suitability of the approach to stabilize curcumin and increase its bioaccessibility was assessed. Results showed that the maximum loading capacity of the liposomes was around 1.5% of curcumin, although the loading capacity of the hybrid microencapsulation structures increased with the curcumin content by incorporation of curcumin microcrystals upon electrospraying. Microencapsulation of curcumin within the proposed hybrid structures significantly increased its bioaccessibility (∼1.7-fold) compared to the free compound, and could successfully stabilize it against degradation in PBS (pH = 7.4). The proposed approach thus proved to be a promising alternative to produce powder-like functional ingredients.
Versión del editorhttps://doi.org/10.1016/j.foodchem.2017.04.133
URIhttp://hdl.handle.net/10261/150168
DOI10.1016/j.foodchem.2017.04.133
ISSN0308-8146
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