English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/148936
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:


Optimized polarization build-up times in dissolution DNP-NMR using a benzyl amino derivative of BDPA

AuthorsMuñoz Gómez, José L ; Monteagudo, Eva; Lloveras, Vega ; Parella, Teodor; Veciana, Jaume ; Vidal Gancedo, José
KeywordsDynamic nuclear-polarization
Enhanced NMR
Issue Date22-Feb-2016
PublisherRoyal Society of Chemistry (UK)
CitationRSC Advances 6(32): 27077-27082 (2016)
AbstractThe synthesis of two novel BDPA-like radicals, a benzyl amino (BAm-BDPA, 7) and a cyano (CN-BDPA, 5) derivative, is reported and their behaviour as polarizing agents for fast dissolution Dynamic Nuclear Polarization (DNP) is evaluated. The radical 7 is a promising candidate for DNP studies since it is soluble in neat [1-13C]pyruvic acid (PA), and therefore the use of an additional glassing agent for sample homogeneity is avoided. In addition, a 60 mM sample of 7 offers optimum 13C NMR signal enhancements using fairly short polarization times (about 1800 s). It is shown that DNP-NMR measurements using 7 can be performed much more efficiently in terms of the signal enhancement per polarization build-up time unit than when using the reference OX63 or BDPA radicals. These enhanced features are translated to a substantial reduction of polarization times that represents an optimum temporary use of the DNP polarizer and allow economized liquid helium consumption.
Publisher version (URL)http://dx.doi.org/10.1039/C6RA00635C
Appears in Collections:(ICMAB) Artículos
Files in This Item:
File Description SizeFormat 
Munoz_RCSAdv_2016_postprint.pdf493,58 kBAdobe PDFThumbnail
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.