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Título: | Allatostatic neuropeptides from the cockroach Blattella germanica (L.) (Dictyoptera, Blattellidae). Identification, immunolocalization and activity |
Autor: | Bellés, Xavier CSIC ORCID ; Maestro, José L. CSIC ORCID ; Piulachs, Maria-Dolors CSIC ORCID ; Johnsen, Anders H.; Duve, Hanne; Thorpe, Alan J. | Palabras clave: | Corpora allata Juvenile hormone Allatostatin |
Fecha de publicación: | 21-oct-1994 | Editor: | Elsevier | Citación: | Regulatory Peptides 53(3): 237-247 (1994) | Resumen: | Four allatostatic neuropeptides were isolated from extracts of the brain of the cockroach Blattella germanica. The primary structures of these peptides were assigned as Leu-Tyr-Asp-Phe-Gly-Leu-NH2 (BLAST-1), Asp-Arg-Leu-Tyr-Ser-Phe-Gly-Leu-NH2 (BLAST-2), Ala-Gly-Ser-Asp-Gly-Arg-Leu-Tyr-Ser-Phe-Gly-Leu-NH2 (BLAST-3) and Ala-Pro-Ser-Ser-Ala-Gln-Arg-Leu-Tyr-Gly-Phe-Gly-Leu-NH2 (BLAST-4). Each of the peptides showed C-terminal amino acid sequence similarity to cockroach allatostatins and blowfly callatostatins. The four peptides inhibited in vitro juvenile hormone production by corpora allata from virgin females of B. germanica. Immunoreactivity against allatostatins was seen in the lateral neurosecretory neurons and in the axonal pathway leading to the corpora allata. | Versión del editor: | http://doi.org/10.1016/0167-0115(94)90172-4 | URI: | http://hdl.handle.net/10261/147947 | DOI: | 10.1016/0167-0115(94)90172-4 | Identificadores: | issn: 0167-0115 |
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