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Title

Visual decline in aged mice is delayed by proinsulin

AuthorsDe la Rosa, Enrique J. ; Hernández-Pinto, Alberto M. ; Vicente, Javier; Ramírez, Laura ; Ayuso, Eduard; Boya, Patricia ; Hernández-Sánchez, Catalina ; Bosch, Fátima; Villa, Pedro de la
Issue DateMay-2016
PublisherAssociation for Research in Vision and Ophthalmology
CitationARVO 2016 (Seatle) "Research: A Vision for Hope" (pág.3)
AbstractVisual decline is normally associated to the aging process.We search for cellular and molecular processes associated to normal aging. In addition, we have previously shown that human proinsulin (hPi) delays vision loss, as determined by electroretinography (ERG),and retinal degeneration, as determined by photoreceptor counting,in the rd10 mouse and the P23H rat models of Retinitis Pigmentosa.Our aim is to reveal additional potential benets of a hPi-based treatment in the aged retina.
Description1 p.
Publisher version (URL)https://cld.bz/YtGLFmy#
URIhttp://hdl.handle.net/10261/147730
Appears in Collections:(CIB) Comunicaciones congresos
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