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Natural insecticides: Structure diversity, effects and structure-activity relationships. A case study

AutorGonzález-Coloma, Azucena ; Reina, Matías ; Gutiérrez, Carmen ; Fraga, Braulio M.
Fecha de publicación2002
CitaciónStudies in Natural Products Chemistry 26(7): 849-879 (2002)
ResumenFor the past ten years our research group has been working on bioactive natural products with insecticidal effects. We have focused mainly on the flora of the Canarian Archipelago because of its rich biodiversity (Lauraceae, Compositae, Boraginaceae). Additionally, we have carried out comparative studies of species belonging to these plant families from different geographical origins (Japan, Chile). As a result of these studies we have isolated bioactive compounds belonging to several chemical classes (sesquiterpenes, diterpenes, lignans, diterpenoid alkaloids, pyrrolizidine alkaloids) with selective modes of action and low toxicity. The structure-activity relationships of these compounds have also been established. In this chapter we will present the structures and biological effects of these compounds according to their chemical classes as follows:
- Diterpene ryanodanes and isoryanodanes from Lauraceae species
- Lignans from Lauraceae species
- Sesquiterpenes from Compositae species
- Diterpene alkaloids from Ranunculaceae species
- Pyrrolizidine alkaloids from Compositae and Boraginaceae species
Descripción31 pages.-- Issue title: "Bioactive Natural Products".
Versión del editorhttp://dx.doi.org/10.1016/S1572-5995(02)80020-5
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