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Title

Boronic acid-modified alginate enables direct formation of injectable, self-healing and multistimuli-responsive hydrogels

AuthorsPettignano, Asja; Grijalvo, Santiago CSIC ORCID; Häring, Marleen; Eritja Casadellà, Ramón CSIC ORCID ; Bernardi, Luca; Tanchoux, Nathalie; Quignard, Françoise; Díaz Díaz, David CSIC ORCID
KeywordsBoronic acid
Biocompatible hydrogels
Issue Date27-Feb-2017
PublisherRoyal Society of Chemistry (UK)
CitationChemical Communications 53(23): 3350-3353 (2017)
AbstractOne-step functionalization of alginate with boronic acid groups allowed spontaneous formation of biocompatible hydrogels under basic conditions without additional complementary molecules or crosslinking agents. The dynamic nature of boronate ester bonds formed with vicinal diols present on alginate pyranose rings provided remarkable self-healing, injectable and multi-stimuli responsive properties to the material.
Publisher version (URL)10.1039/C7CC00765E
URIhttp://hdl.handle.net/10261/147418
DOIhttp://dx.doi.org/10.1039/C7CC00765E
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