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Handling of wild ruminants in level-3 biosafety facilities

AutorLópez-Olvera, Jorge R. ; Lorca-Oró, Cristina; Falconi, Caterina; Marco, Ignasi; García-Bocanegra, Ignacio; Mentaberre, Gregorio; Cabezón, Óscar; Pujols, Joan; Domingo, Mariano
Fecha de publicación2012
Citación61st WDA/10th EWDA (2012)
ResumenExperimental infection is the most reliable way to study the relationship between infectious agents and their hosts, including pathogenesis of diseases, pathogen excretion and transmission, comparative analysis of strains virulence, immune response and genetic resistance to infections, and vaccine testing, among others. All this information is needed when trying to accurately determine the epidemiological importance of a given host species for a given disease. Nevertheless, experimental infection studies in wild ungulates are scarce, due to the challenge of handling these species in constrained spaces, as well as the stress-associated risks for the animals, which may also affect the results of the study. The aim of this communication is to present the methodology of four experimental infections carried out in three different species of wild ungulate species; two experimental infections with bluetongue virus (BTV) in red deer (Cervus elaphus), one BTV experimental infection in Spanish ibex (Capra pyrenaica), and one experimental infection with chamois Border Disease Virus (ch-BDV) in Southern chamois (Rupicapra pyrenaica). Facilities modification, handling procedures, drugs and dosages administered (including sedatives and longacting neuroleptics), restraint techniques, and sample collection procedures used allowed a safe handling (for both the animals and the operators) and the fulfilment of the objectives of all four experimental infections.
DescripciónResumen del trabajo presentado a la 61st Wildlife Disease Association and 10th Biennial European Wildlife Disease Association: "convergence in wildlife health", celebrada en Lyon (Francia) del 23 al 27 de julio de 2012.-- et al.
URIhttp://hdl.handle.net/10261/146793
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