Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/143891
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Anticipating hyperthermia efficiency of magnetic colloids by a semi-empirical model: a tool to help medical decisions |
Autor: | Fernández van Raap, Marcela B.; Coral, Diego Fernando; Si-Ming, Yu; Muñoz, Guillermo Arturo; Sánchez, Francisco; Roig Serra, Anna CSIC ORCID | Fecha de publicación: | 7-feb-2017 | Editor: | Royal Society of Chemistry (UK) | Citación: | Physical Chemistry Chemical Physics:10.1039/C6CP08059F (2017) | Resumen: | Magnetic hyperthermia, a modality that uses radio frequency heating assisted with single-domain magnetic nanoparticles, is becoming established as a powerful oncological therapy. Much improvement in nanomateriales development, to enhance their heating efficiency by tuning the magnetic colloids properties, has been achieved. However, methodological standardization to accurately and univocally determine the colloids properties required to numerically reproduce specific heating efficiency using analytical expressions still holds. Thus, anticipating the hyperthermic performances of magnetic colloids entails high complexity due to polydispersity, aggregation and dipolar interaction always present in real materials to a more or lesser degree. Here, by numerically simulating experimental results and using real biomedical aqueous colloids, we analyse and compared several approaches to reproduce experimental specific absorption rate values. Then, we show that relaxation time, determined using a representative mean activation energy consistently derived from four independent experiments accurately reproduces experimental heating efficiencies. Moreover, the so-derived relaxation time can be used to extrapolate the heating performance of the magnetic nanoparticles to other field conditions within the framework of the linear response theory. We thus present a practical tool that may truly aid the design of medical decisions. | Versión del editor: | http://dx.doi.org/10.1039/C6CP08059F | URI: | http://hdl.handle.net/10261/143891 | DOI: | 10.1039/C6CP08059F | ISSN: | 1463-9076 |
Aparece en las colecciones: | (ICMAB) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Fernandez_PhysChemChemPhys_2017_postprint.pdf | 1,47 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
WEB OF SCIENCETM
Citations
11
checked on 25-feb-2024
Page view(s)
437
checked on 24-abr-2024
Download(s)
251
checked on 24-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.