English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/143475
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:

Title

Phage lytic proteins: Biotechnological applications beyond clinical antimicrobials

AuthorsRodríguez, Lorena ; Gutiérrez, Diana ; Donovan, David M.; Martínez Fernández, Beatriz ; Rodríguez González, Ana ; García Suárez, María Pilar
KeywordsNanotechnology
Endolysins
Pathogen detection
Vaccines
Virion-associated peptidoglycan hydrolases
Food safety
Biotechnology
Disinfection
Issue Date2016
PublisherTaylor & Francis
CitationCritical Reviews in Biotechnology 36: 542-552 (2016)
AbstractMost bacteriophages encode two types of cell wall lytic proteins: endolysins (lysins) and virion-associated peptidoglycan hydrolases. Both enzymes have the ability to degrade the peptidoglycan of Gram-positive bacteria resulting in cell lysis when they are applied externally. Bacteriophage lytic proteins have a demonstrated potential in treating animal models of infectious diseases. There has also been an increase in the study of these lytic proteins for their application in areas such as food safety, pathogen detection/diagnosis, surfaces disinfection, vaccine development and nanotechnology. This review summarizes the more recent developments, outlines the full potential of these proteins to develop new biotechnological tools and discusses the feasibility of these proposals.
Publisher version (URL)https://doi.org/10.3109/07388551.2014.993587
URIhttp://hdl.handle.net/10261/143475
DOIhttp://dx.doi.org/10.3109/07388551.2014.993587
Identifiersissn: 1549-7801
Appears in Collections:(IPLA) Artículos
Files in This Item:
File Description SizeFormat 
Phage lytic proteins-RodríguezRubio.pdf709,19 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.