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Detection of RHDV strains in the Iberian hare (Lepus granatensis): earliest evidence of rabbit lagovirus cross-species infection

AuthorsLopes, Ana M.; Pinheiro, Ana; Alves, Paulo C.; Esteves, Pedro J.; Abrantes, Joana
Issue Date2014
PublisherBioMed Central
CitationVeterinary Research 45: 94 (2014)
AbstractRabbit hemorrhagic disease virus (RHDV) is a highly lethal Lagovirus, family Caliciviridae, that threatens European rabbits (Oryctolagus cuniculus). Although a related virus severely affects hares, cross-species infection was only recently described for new variant RHDV in Cape hares (Lepus capensis mediterraneus). We sequenced two strains from dead Iberian hares (Lepus granatensis) collected in the 1990s in Portugal. Clinical signs were compatible with a Lagovirus infection. Phylogenetic analysis of the complete capsid gene positioned them in the RHDV genogroup that circulated on the Iberian Peninsula at that time. This is the earliest evidence of RHDV affecting a species other than European rabbits.
DescriptionThis is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.
Publisher version (URL)https://doi.org/10.1186/s13567-014-0094-7
Identifiersdoi: 10.1186/s13567-014-0094-7
e-issn: 1297-9716
issn: 0928-4249
Appears in Collections:(IREC) Artículos
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