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Título

Virtual Screening Approaches towards the Discovery of Toll-Like Receptor Modulators

AutorPérez-Regidor, Lucía; Zarioh, Malik; Ortega, Laura; Martín-Santamaría, Sonsoles
Fecha de publicación9-sep-2016
EditorMultidisciplinary Digital Publishing Institute
CitaciónInternational Journal of Molecular Sciences 17(9): 1508 (2016)
ResumenThis review aims to summarize the latest efforts performed in the search for novel chemical entities such as Toll-like receptor (TLR) modulators by means of virtual screening techniques. This is an emergent research field with only very recent (and successful) contributions. Identification of drug-like molecules with potential therapeutic applications for the treatment of a variety of TLR-regulated diseases has attracted considerable interest due to the clinical potential. Additionally, the virtual screening databases and computational tools employed have been overviewed in a descriptive way, widening the scope for researchers interested in the field.
URIhttp://hdl.handle.net/10261/142085
DOIhttp://dx.doi.org/10.3390/ijms17091508
Identificadoresdoi: 10.3390/ijms17091508
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