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Title

FRODOCK 2.0: Fast protein-protein docking server

AuthorsRamirez-Aportela, E.; López-Blanco, José R.; Chacón, Pablo
Issue Date2016
CitationBioinformatics 32: 2386- 2388 (2016)
AbstractThe prediction of protein-protein complexes from the structures of unbound components is a challenging and powerful strategy to decipher the mechanism of many essential biological processes. We present a user-friendly protein-protein docking server based on an improved version of FRODOCK that includes a complementary knowledge-based potential. The web interface provides a very effective tool to explore and select protein-protein models and interactively screen them against experimental distance constraints. The competitive success rates and efficiency achieved allow the retrieval of reliable potential protein-protein binding conformations that can be further refined with more computationally demanding strategies. Availability and Implementation: The server is free and open to all users with no login requirement at http://frodock.chaconlab.org.
URIhttp://hdl.handle.net/10261/142002
DOI10.1093/bioinformatics/btw141
Identifiersdoi: 10.1093/bioinformatics/btw141
issn: 1460-2059
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