English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/137371
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Title

A novel route for the diastereoselective synthesis of dispiro[tetrahydroquinoline-bis(2,2-dimethyl[1,3]dioxane-4,6-dione)] derivatives via a one-pot domino multicomponent reaction of arylamines, aromatic aldehydes, and meldrum's acid

AuthorsLashkari, Mojtaba; Maghsoodlou, Malek Taher; Hazeri, Nourallah; García-Granda, Santiago ; Torre-Fernández, Laura
Issue Date2015
PublisherJohn Wiley & Sons
CitationJournal of Heterocyclic Chemistry 52(3): 873-879 (2015)
AbstractA protocol has been developed for the diastereoselective synthesis of dispiro[tetrahydroquinoline-bis(2,2-dimethyl[1,3] dioxane-4,6-dione)] derivatives via a one-pot domino multicomponent reaction of arylamines, aromatic aldehydes, and Meldrum's acid for the first time. The products, with remarkable diastereoselectivity, were successfully synthesized in acetic acid media in ambient temperature along with the suggested mechanism through combination of domino Knoevenagel, Michael, and Diels–Alder reactions. The products have been characterized by IR, mass, 1H NMR, 13C NMR spectroscopy, and elemental analyses. The stereoselectivity of compounds was established with crystallography and NMR spectroscopy.
URIhttp://hdl.handle.net/10261/137371
DOI10.1002/jhet.1984
Identifiersdoi: 10.1002/jhet.1984
issn: 0022-152X
e-issn: 1943-5193
Appears in Collections:(CINN) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.