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An efficient green synthesis of dispirohydroquinolines via a diastereoselective one-pot eight-component reaction

AuthorsSalahi, Sajjad; Maghsoodlou, Malek Taher; Hazeri, Nourallah; Lashkari, Mojtaba; García-Granda, Santiago CSIC ORCID CVN; Torre-Fernández, Laura
KeywordsCitric acid
Eight-component reaction
Meldrum's acid
Issue Date2015
CitationChinese Journal of Catalysis 36(7): 1023-1028 (2015)
AbstractThe one-pot eight-component reaction between Meldrum's acid, an aromatic aldehyde, and an aryl amine was achieved in the presence of citric acid catalyst. The corresponding dispirohydroquinolines were obtained in good yields with excellent diastereoselectivity. This method is a combination of the Knoevenagel and Michael reactions.
Identifiersdoi: 10.1016/S1872-2067(15)60846-4
issn: 1872-2067
Appears in Collections:(CINN) Artículos
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