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Towards a non-invasive ultrasound method for the diagnosis of neonatal and infant meningitis

AuthorsJiménez, Xavier; Shukla, Shiva Kant; Martínez-Graullera, Óscar ; Ibáñez Rodríguez, Alberto; Parrilla Romero, Montserrat; Elvira Segura, Luis
high-frequency ultrasounds
cell count
Issue Date4-Nov-2015
CitationPoster presentado en : Meningitis Research Foundation’s 10th international conference: meningitis and septicaemia in children and adults, 4-5 november 2015. Royal Society of Medicine, London, UK
AbstractLumbar Puncture (LP) is currently used to draw a sample of cerebrospinal fluid (CSF) and test for potentially lethal Bacterial Meningitis (BM) in infants (<1yr). Increased CSF cellularity is highly indicative of BM and triggers medication for the patient. In developed countries, 95% of LPs for BM in infants return negative. In developing countries, LPs are rarely available, with 50% of infants with BM dying from the disease. We propose using high-frequency ultrasounds (HFUS) to non-invasively determine CSF cell concentration through the fontanel. The aim of this study is to assess the capabilities of HFUS on a fontanel phantom involving mock CSF with varying leukocyte concentration and pig tissue.
Publisher version (URL)http://www.meningitis.org/posters2015
Appears in Collections:(ITEFI) Cursos-Material didáctico
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