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Título: | The Golgi apparatus: insights from filamentous fungi |
Autor: | Pantazopoulou, Areti CSIC ORCID | Palabras clave: | Aspergillus nidulans Filamentous fungi Golgi apparatus Intracellular traffic Secretion |
Fecha de publicación: | 1-mar-2016 | Editor: | Mycological Society of America | Citación: | Mycologia 108(3):603-22 (2016) | Resumen: | Cargo passage through the Golgi, albeit an undoubtedly essential cellular function, is a mechanistically unresolved and much debated process. Although the main molecular players are conserved, diversification of the Golgi among different eukaryotic lineages is providing us with tools to resolve standing controversies. During the past decade the Golgi apparatus of model filamentous fungi, mainly Aspergillus nidulans, has been intensively studied. Here an overview of the most important findings in the field is provided. Golgi architecture and dynamics, as well as the novel cell biology tools that were developed in filamentous fungi in these studies, are addressed. An emphasis is placed on the central role the Golgi has as a crossroads in the endocytic and secretory-traffic pathways in hyphae. Finally the major advances that the A. nidulans Golgi biology has yielded so far regarding our understanding of key Golgi regulators, such as the Rab GTPases RabCRab6 and RabERab11, the oligomeric transport protein particle, TRAPPII, and the Golgi guanine nucleotide exchange factors of Arf1,GeaAGBF1/Gea1 and HypBBIG/Sec7, are highlighted. | Descripción: | 20 p.-2 fig. | Versión del editor: | http://dx.doi.org/ 10.3852/15-309 | URI: | http://hdl.handle.net/10261/133182 | DOI: | 10.3852/15-309 | ISSN: | 0027-5514 | E-ISSN: | 1557-2536 |
Aparece en las colecciones: | (CIB) Artículos |
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MYCOLOGIA_2016.pdf | Artículo principal | 1,07 MB | Adobe PDF | Visualizar/Abrir |
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