English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/133048
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:


Allene-Based Gold-Catalyzed Stereodivergent Synthesis of Azapolycyclic Derivatives of Unusual Structure

AuthorsAlcaide, Benito ; Almendros, Pedro ; Martín-Montero, Raúl; Ruiz, M. Pilar
Synthetic methods
Heterocyclic compounds
Issue Date2016
PublisherJohn Wiley & Sons
CitationAdvanced Synthesis and Catalysis 358: 1469-1477 (2016)
AbstractThe present study provides insights into the manner in which the configuration of β-aminoallene precursors affects their gold-catalyzed cyclization reactions. The reactivity can be switched by using indolizidinone-tethered β-aminoallenes bearing the syn- or the anti-disposition of both protons at the α- and β-allenic stereocenters. Fused heterocycles (seven examples, 60-75% yields) are obtained from the syn-precursors, while a dimerization-aminoketalization-spirocyclization sequence to afford benzo[b]pyrrolo[3,2,1-ij][1,7]naphthyridin-1-ones (four examples, 34-48% yields) can be achieved starting from their anti-isomers.
Publisher version (URL)http://dx.doi.org/10.1002/adsc.201501145
Identifiersdoi: 10.1002/adsc.201501145
issn: 1615-4150
e-issn: 1615-4169
Appears in Collections:(IQOG) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.