English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/132322
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Enhanced antibody recognition with a magneto-optic surface plasmon resonance (MO-SPR) sensor

AutorManera, Maria Grazia; Ferreiro-Vila, Elías ; García-Martín, José Miguel ; García-Martín, Antonio ; Rella, Roberto
Palabras claveActive plasmonics
Surface Plasmon Resonance (SPR)
Transducing layer
Magneto-optic
Fecha de publicación15-ago-2014
EditorElsevier
CitaciónBiosensors and Bioelectronics 58: 114-120 (2014)
ResumenA comparison between sensing performance of traditional SPR (Surface Plasmon Resonance) and magneto-optic SPR (MOSPR) transducing techniques is presented in this work. MOSPR comes from an evolution of traditional SPR platform aiming at modulating Surface Plasmon wave by the application of an external magnetic field in transverse configuration. Previous work demonstrated that, when the Plasmon resonance is excited in these structures, the external magnetic field induces a modification of the coupling of the incident light with the Surface Plasmon Polaritons (SPP). Besides, these structures can lead to an enhancement in the magneto-optical (MO) activity when the SPP is excited. This phenomenon is exploited in this work to demonstrate the possibility to use the enhanced MO signal as proper transducer signal for investigating biomolecular interactions in liquid phase. To this purpose, the transducer surface was functionalized by thiol chemistry and used for recording the binding between Bovine Serum Albumin molecules immobilized onto the surface and its complementary target. Higher sensing performance in terms of sensitivity and lower limit of detection of the MOSPR biosensor with respect to traditional SPR sensors is demonstrated. © 2014 Elsevier B.V.
Versión del editorhttp://dx.doi.org/10.1016/j.bios.2014.02.003
URIhttp://hdl.handle.net/10261/132322
DOI10.1016/j.bios.2014.02.003
Identificadoresissn: 1873-4235
Aparece en las colecciones: (IMN-CNM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
accesoRestringido.pdf15,38 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.