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New terpenoids from the brown alga Stypopodium zonale

AuthorsDorta, Enrique ; Cueto, Mercedes ; Brito, Inmaculada ; Darias, José
Issue Date2-Oct-2002
PublisherAmerican Chemical Society
American Society of Pharmacognosy
CitationJournal of Natural Products 65(11): 1727-1730 (2002)
AbstractThree new terpenoids, 1a−3a, and the known metabolites atomaric acid, stypoquinonic acid, and 5'a-desmethyl-5'-acetylatomaric acid have been isolated from the tropical brown alga Stypopodium zonale. The structures and relative stereochemistry of the methyl ester of 1a−3a were determined by spectral methods. The methyl ester of 3a exhibits in vitro cytotoxic activity against human lung and colon carcinoma.
Description4 pages, 2 figures, 1 table.-- PMID: 12444716 [PubMed].-- Printed version published Nov 22, 2002.
Publisher version (URL)http://dx.doi.org/10.1021/np020090g
Appears in Collections:(IPNA) Artículos
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