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Synthesis and Chemistry of Tetronic Acids

AuthorsTejedor, David ; García-Tellado, Fernando
Issue Date2004
PublisherOrganic Preparations and Procedures
CitationOrganic Preparations and Procedures International 36: 33-59 (2004)
AbstractTetronic acids (4-hydroxy-2(5H)-furanones) form a subclass of β-hydroxybutenolides with the generic structure 1. The best known members of this family are vitamin C (ascorbic acid) 2 and pennicillic acid 3. A great number of these compounds and their metabolites are found in many natural products, which exhibit a wide array of biological properties. The aim of this review is to cover the current synthetic methodologies developed to build these molecules and their specific chemistry more than biological and pharmaceutical aspects of these products.
Description28 pages, 2 figures, 38 schemes.
Publisher version (URL)http://www.oppint.com/indices.html
Appears in Collections:(IPNA) Artículos
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