English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/130886
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Love-Wave Sensors Combined with Microfluidics for Fast Detection of Biological Warfare Agents

AutorMatatagui, D.; Fontecha, J. L.; Fernández, María Jesús; Gràcia Tortadès, Isabel; Cané Ballart, Carles; Santos Blanco, José Pedro; Horrillo, M. C.
Palabras clavebiological warfare agent
BWA
love-wave
sensor acoustic wave
SAW
biosensor
immunosensor
microfluidics
bacteriophage
Fecha de publicación15-jul-2014
EditorMultidisciplinary Digital Publishing Institute
CitaciónSensors 14: 12658-12669 (2014)
ResumenThe following paper examines a time-efficient method for detecting biological warfare agents (BWAs). The method is based on a system of a Love-wave immunosensor combined with a microfluidic chip which detects BWA samples in a dynamic mode. In this way a continuous flow-through of the sample is created, promoting the reaction between antigen and antibody and allowing a fast detection of the BWAs. In order to prove this method, static and dynamic modes have been simulated and different concentrations of BWA simulants have been tested with two immunoreactions: phage M13 has been detected using the mouse monoclonal antibody anti-M13 (AM13), and the rabbit immunoglobulin (Rabbit IgG) has been detected using the polyclonal antibody goat anti-rabbit (GAR). Finally, different concentrations of each BWA simulants have been detected with a fast response time and a desirable level of discrimination among them has been achieved.
Versión del editorhttp://dx.doi.org/10.3390/s140712658
URIhttp://hdl.handle.net/10261/130886
DOI10.3390/s140712658
ISSN1424-8220
Aparece en las colecciones: (ITEFI) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Love-Wave_Sensors_Matatagui.pdf1,82 MBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.