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Título: | Case Report: Resolution of submacular haemorrhage secondary to exudative age-related macular degeneration after a single intravitreal dobesilate injection |
Autor: | Cuevas, Pedro; Outeiriño, Luis A.; Azanza, Carlos; Angulo, Javier; Giménez-Gallego, Guillermo CSIC | Fecha de publicación: | 9-dic-2013 | Editor: | Faculty of 1000 | Citación: | F1000Research 2: 271 (2013) | Resumen: | [Introduction] Submacular haemorrhage is not an unusual cause of acute central vision loss, particularly in older people. It may be caused by a number of conditions, most common of which is exudative age-related madular degeneration. In patients affected by this type of macular degeneration, choroidal neovascularization extends into the subretinal space, producing substantial bleeding in approximately 17% of cases, resulting in large haemorrhages in the subretinal space that detach the neurosensory retina from the supporting retinal pigment epithelial (RPE) layer. This leads to substantial vision loss because of a relatively fast process of extensive photoreceptor atrophy in the overlying neuroretina and formation of macular scars [Case presentation] We describe a patient with submacular haemorrhage secondary to exudative age-related macular degeneration, treated with intravitreal injection of dobesilate. Two months later, visual acuity in the treated eye reached 0.50 with a significant improvement of the distortion and an anatomical resolution of the haemorrhage, as confirmed by optical coherence tomography. [Conclusions] Submacular haemorrhage secondary to exudative age-related macular degeneration can be successfully treated with intravitreal dobesilate. To our knowledge, this is the first case reporting a resolution of submacular haemorrhage after a single dobesilate injection. |
Versión del editor: | http://dx.doi.org/10.12688/f1000research.2-271.v1 | URI: | http://hdl.handle.net/10261/130882 | DOI: | 10.12688/f1000research.2-271.v1 | ISSN: | 2046-1402 |
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