English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/129567
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Genome-wide epigenetic cross-talk between DNA methylation and H3K27me3 in zebrafish embryos

AutorCalle-Mustienes, Elisa de la ; Gómez-Skarmeta, José Luis ; Bogdanovic, Ozren
Palabras clavePolycomb
Zebrafish
Embryogenesis
DNA methylation
Fecha de publicación2015
EditorElsevier
CitaciónGenomics Data 6: 7-9 (2015)
ResumenDNA methylation and histone modifications are epigenetic marks implicated in the complex regulation of vertebrate embryogenesis. The cross-talk between DNA methylation and Polycomb-dependent H3K27me3 histone mark has been reported in a number of organisms [1-7] and both marks are known to be required for proper developmental progression. Here we provide genome-wide DNA methylation (MethylCap-seq) and H3K27me3 (ChIP-seq) maps for three stages (dome, 24. hpf and 48. hpf) of zebrafish (Danio rerio) embryogenesis, as well as all analytical and methodological details associated with the generation of this dataset. We observe a strong antagonism between the two epigenetic marks present in CpG islands and their compatibility throughout the bulk of the genome, as previously reported in mammalian ESC lines (Brinkman et al., 2012). Next generation sequencing data linked to this project have been deposited in the Gene Expression Omnibus (GEO) database under accession numbers GSE35050 and GSE70847.
DescripciónUnder a Creative Commons license.
Versión del editorhttp://dx.doi.org/10.1016/j.gdata.2015.07.020
URIhttp://hdl.handle.net/10261/129567
DOI10.1016/j.gdata.2015.07.020
Identificadoresdoi: 10.1016/j.gdata.2015.07.020
issn: 2213-5960
Aparece en las colecciones: (CABD) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
H3K27me3.pdf567,86 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.