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Escherichia coli carbon source metabolism affects longevity of its predator Caenorhabditis elegans

AutorBrokate-Llanos, Ana María ; Garzón, Andrés ; Muñoz, Manuel J.
Palabras clavePathogenicity
Escherichia coli
Metabolism
Sugar
Lifespan
Caenorhabditis elegans
Fecha de publicación2014
EditorElsevier
CitaciónMechanisms of Ageing and Development 141-142: 22-25 (2014)
ResumenNutrition is probably the most determinant factor affecting aging. Microorganisms of the intestinal flora lay in the interface between available nutrients and nutrients that are finally absorbed by multicellular organisms. They participate in the processing and transformation of these nutrients in a symbiotic or commensalistic relationship. In addition, they can also be pathogens. Alive Escherichia coli OP50 are usually used to culture the bacteriovorus nematode Caenorhabditis elegans. Here, we report a beneficial effect of low concentration of saccharides on the longevity of C. elegans. This effect is only observed when the bacterium can metabolize the sugar, suggesting that physiological changes in the bacterium feeding on the saccharides are the cause of this beneficial effect.
URIhttp://hdl.handle.net/10261/129293
DOI10.1016/j.mad.2014.09.001
Identificadoresdoi: 10.1016/j.mad.2014.09.001
e-issn: 1872-6216
issn: 0047-6374
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