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Título

Coenzyme Q10 in salivary cells correlate with blood cells in Fibromyalgia: Improvement in clinical and biochemical parameter after oral treatment

AutorCordero, Mario D. ; Santos-García, Rocío; Bermejo-Jover, David; Sánchez-Domínguez, Benito; Jaramillo-Santos, María Reyes; Bullón, Pedro
Palabras claveFibromyalgia
Coenzyme Q10
Salivary cells
Blood mononuclear cells
Fecha de publicación2012
EditorElsevier
CitaciónClinical Biochemistry 45(6): 509-511 (2012)
Resumen[Objective]: We have determined Coenzyme Q10 (CoQ10) levels in salivary cells (SCs) and mononuclear blood cells (BMCs) from Fibromyalgia (FM), and we study the influence of oral CoQ10 supplementation on cells levels and clinical symptoms. [Methods]: CoQ10 was determined by high-performance liquid chromatography (HPLC). Ten patients were supplemented daily with 300 mg of CoQ10 during 3 months. [Results]: CoQ10 were reduced in both cell models. Oral supplementation showed an improvement in clinical symptoms and restored levels. [Conclusions]: Patients with FM showed an important dysfunction in CoQ10 levels and might benefit from oral supplementation.
Versión del editorhttp://dx.doi.org/10.1016/j.clinbiochem.2012.02.001
URIhttp://hdl.handle.net/10261/129085
DOI10.1016/j.clinbiochem.2012.02.001
ISSN0009-9120
E-ISSN1873-2933
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