English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/128740
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Differences in the toxin profiles of Alexandrium ostenfeldii (Dinophyceae) strains isolated from different geographic origins: Evidence of paralytic toxin, spirolide, and gymnodimine

AuthorsSalgado, P.; Riobó, Pilar ; Rodríguez, Francisco; Franco, José M. ; Bravo, Isabel
KeywordsAlexandrium ostenfeldii
Toxin profile
Paralytic toxin
Spirolide
Gymnodimine
Issue Date2015
PublisherElsevier
CitationToxicon 103: 85-98 (2015)
AbstractAmong toxin-producing dinoflagellates of the genus Alexandrium, Alexandrium ostenfeldii is the only species able to produce paralytic shellfish poisoning (PSP) toxins, spirolides (SPXs) and gymnodimines (GYMs). In this study we characterized and compared three A. ostenfeldii strains isolated from the Baltic, Mediterranean, and southern Chile Seas with respect to their toxin profiles, morphology, and phylogeny. Toxin analyses by HPLC–FD and LC–HRMS revealed differences in the toxin profiles of the three strains. The PSP toxin profiles of the southern Chile and Baltic strains were largely the same and included gonyautoxin (GTX)-3, GTX-2, and saxitoxin (STX), although the total PSP toxin content of the Chilean strain (105.83 ± 72.15 pg cell−1) was much higher than that of the Baltic strain (4.04 ± 1.93 pg cell−1). However, the Baltic strain was the only strain that expressed detectable amounts of analogues of GYM-A and GYM-B/-C (48.27 ± 26.12 pg GYM-A equivalents cell−1). The only toxin expressed by the Mediterranean strain was 13-desmethyl SPX-C (13dMeC; 2.85 ± 4.76 pg cell−1). Phylogenetic analysis based on the LSU rRNA showed that the studied strains belonged to distinct molecular clades. The toxin profiles determined in this study provide further evidence of the taxonomic complexity of this species
Description14 páginas, 7 figuras, 5 tablas
Publisher version (URL)http://dx.doi.org/10.1016/j.toxicon.2015.06.015
URIhttp://hdl.handle.net/10261/128740
DOI10.1016/j.toxicon.2015.06.015
ISSN0041-0101
E-ISSN1879-3150
Appears in Collections:(IIM) Artículos
Files in This Item:
File Description SizeFormat 
Differences_toxin profiles_Alexandrium.pdf767,59 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.