English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/128740
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Differences in the toxin profiles of Alexandrium ostenfeldii (Dinophyceae) strains isolated from different geographic origins: Evidence of paralytic toxin, spirolide, and gymnodimine

AutorSalgado, P.; Riobó, Pilar ; Rodríguez, Francisco; Franco, José M. ; Bravo, Isabel
Palabras claveAlexandrium ostenfeldii
Toxin profile
Paralytic toxin
Spirolide
Gymnodimine
Fecha de publicación2015
EditorElsevier
CitaciónToxicon 103: 85-98 (2015)
ResumenAmong toxin-producing dinoflagellates of the genus Alexandrium, Alexandrium ostenfeldii is the only species able to produce paralytic shellfish poisoning (PSP) toxins, spirolides (SPXs) and gymnodimines (GYMs). In this study we characterized and compared three A. ostenfeldii strains isolated from the Baltic, Mediterranean, and southern Chile Seas with respect to their toxin profiles, morphology, and phylogeny. Toxin analyses by HPLC–FD and LC–HRMS revealed differences in the toxin profiles of the three strains. The PSP toxin profiles of the southern Chile and Baltic strains were largely the same and included gonyautoxin (GTX)-3, GTX-2, and saxitoxin (STX), although the total PSP toxin content of the Chilean strain (105.83 ± 72.15 pg cell−1) was much higher than that of the Baltic strain (4.04 ± 1.93 pg cell−1). However, the Baltic strain was the only strain that expressed detectable amounts of analogues of GYM-A and GYM-B/-C (48.27 ± 26.12 pg GYM-A equivalents cell−1). The only toxin expressed by the Mediterranean strain was 13-desmethyl SPX-C (13dMeC; 2.85 ± 4.76 pg cell−1). Phylogenetic analysis based on the LSU rRNA showed that the studied strains belonged to distinct molecular clades. The toxin profiles determined in this study provide further evidence of the taxonomic complexity of this species
Descripción14 páginas, 7 figuras, 5 tablas
Versión del editorhttp://dx.doi.org/10.1016/j.toxicon.2015.06.015
URIhttp://hdl.handle.net/10261/128740
DOI10.1016/j.toxicon.2015.06.015
ISSN0041-0101
E-ISSN1879-3150
Aparece en las colecciones: (IIM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Differences_toxin profiles_Alexandrium.pdf767,59 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.