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Fluid dynamics of establishing left-right patterning in development

AuthorsCartwright, Julyan H. E.; Piro, Nicolás; Piro, Oreste ; Tuval, Idan
KeywordsFluid dynamics
Left–right patterning
Issue Date10-Jun-2008
PublisherJohn Wiley & Sons
CitationBirth Defects Research Part C: Embryo Today 84(2): 95-101 (2008)
AbstractHow does the clockwise motion of tens of monocilia drive a leftward flow in the node? And, as the observed flow is leftward, how is the fluid recirculating within the node, as it must, because the node is a closed structure How does the nodal flow lead to left-right symmetry breaking in the embryo? These questions are within the realm of fluid physics, whose application to the problem of left-right symmetry breaking in vertebrates has led to important advances in the field.
Description7 pages, 5 figures.-- PMID: 18546334 [PubMed].
Full-text version available Open Access at: http://www.damtp.cam.ac.uk/user/idan/PAPERS/EmbryoToday84.pdf
Appears in Collections:(IFISC) Artículos
(IACT) Artículos
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