English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/12842
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Citado 53 veces en Web of Knowledge®  |  Pub MebCentral Ver citas en PubMed Central  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Dendritic size of pyramidal neurons differs among mouse cortical regions

AutorBenavides-Piccione, Ruth ; Hamzei-Sichani, Farid; Ballesteros-Yáñez, Inmaculada; Felipe, Javier de ; Yuste, Rafael
Palabras claveCircuit
Lucifer Yellow
PCA
Cluster analysis
Fecha de publicaciónjul-2006
EditorOxford University Press
CitaciónCerebral Cortex 16(7): 990-1001 (2006)
ResumenNeocortical circuits share anatomical and physiological similarities among different species and cortical areas. Because of this, a ‘canonical’ cortical microcircuit could form the functional unit of the neocortex and perform the same basic computation on different types of inputs. However, variations in pyramidal cell structure between different primate cortical areas exist, indicating that different cortical areas could be built out of different neuronal cell types. In the present study, we have investigated the dendritic architecture of 90 layer II/III pyramidal neurons located in different cortical regions along a rostrocaudal axis in the mouse neocortex, using, for the first time, a blind multidimensional analysis of over 150 morphological variables, rather than evaluating along single morphological parameters. These cortical regions included the secondary motor cortex (M2), the secondary somatosensory cortex (S2), and the lateral secondary visual cortex and association temporal cortex (V2L/TeA). Confirming earlier primate studies, we find that basal dendritic morphologies are characteristically different between different cortical regions. In addition, we demonstrate that these differences are not related to the physical location of the neuron and cannot be easily explained assuming rostrocaudal gradients within the cortex. Our data suggest that each cortical region is built with specific neuronal components.
Descripción12 pages, 7 figures, 3 tables.-- PMID: 16195469 [PubMed].-- Available online Sep 29, 2005.
Versión del editorhttp://dx.doi.org/10.1093/cercor/bhj041
URIhttp://hdl.handle.net/10261/12842
DOI10.1093/cercor/bhj041
ISSN1047-3211 (Print)
1460-2199 (Online)
Aparece en las colecciones: (IC) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Dendritic_size.pdf1,05 MBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 



NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.