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About the vibrational spectroscopy in the diagnosis of Alzheimer's disease | Sobre la espectroscopía vibracional en el diagnóstico de la enfermedad de Alzheimer

AuthorsCarmona, Pedro CSIC; López-Tobar, Eduardo CSIC; Molina, Marina; Toledano Gasca, Adolfo CSIC ORCID
Issue Date2015
PublisherReal Academia Nacional de Farmacia (España)
CitationAnales de la Real Academia Nacional de Farmacia 81: 19- 24 (2015)
AbstractTwo-dimensional correlation vibrational spectroscopy is emerging as an alternative technique to detect relatively small alterations in composition and molecular structure of complex biological systems such as blood plasma resulting from pathological, physical and chemical processes occuring in body. In this paper the main concepts considered in the use of infrared and Raman spectroscopies in their two-dimensional form and their application in the search for markers for the diagnosis of Alzheimer's disease are described. Some examples of representation of spectral markers in ROC curves showing accuracies in classifications of samples greater than 80% are also discussed.
Description6 pags.; 6 figs.
Identifiersissn: 1697-428X
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(IC) Artículos
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