English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/127912
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Engineered bacteria as therapeutic agents

AutorPiñero-Lambea, C.; Ruano Gallego, D.; Fernández, Luis Ángel
Palabras claveBacterial engineering
Bacterial therapies
Cancer
Immune diseases
Synthetic biology
Fecha de publicacióndic-2015
EditorElsevier
CitaciónCurrent Opinion in Biotechnology
ResumenAlthough bacteria are generally regarded as the causative agents of infectious diseases, most bacteria inhabiting the human body are non-pathogenic and some of them can be turned, after proper engineering, into ‘smart’ living therapeutics of defined properties for the treatment of different illnesses. This review focuses on recent developments to engineer bacteria for the treatment of diverse human pathologies, including inflammatory bowel diseases, autoimmune disorders, cancer, metabolic diseases and obesity, as well as to combat bacterial and viral infections. We discuss significant advances provided by synthetic biology to fully reprogram bacteria as human therapeutics, including novel measures for strict biocontainment.
Versión del editorhttp://dx.doi.org/10.1016/j.copbio.2015.05.00
URIhttp://hdl.handle.net/10261/127912
DOI10.1016/j.copbio.2015.05.004
Aparece en las colecciones: (CNB) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
COBIOT-D-15-00008R1.pdf"Artículo principal"696,46 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.