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dc.contributor.authorReina, Matíasen_US
dc.contributor.authorGonzález-Coloma, Azucenaen_US
dc.contributor.authorGutiérrez, Carmenen_US
dc.contributor.authorCabrera, Raimundoen_US
dc.contributor.authorLópez Rodríguez, Matíasen_US
dc.contributor.authorFajardo, Víctoren_US
dc.contributor.authorVillarroel, Luis-
dc.date.accessioned2009-04-28T07:18:55Z-
dc.date.available2009-04-28T07:18:55Z-
dc.date.issued2001-01-26en_US
dc.identifier.citationJournal of Natural Products 64(1): 6-11 (2001)en_US
dc.identifier.issn0163-3864-
dc.identifier.urihttp://hdl.handle.net/10261/12621-
dc.description6 pages, 3 figures, 5 tables.-- PMID: 11170657 [PubMed].-- Available online Dec 5, 2000.-
dc.descriptionSupporting information (6 Suppl. tables) available at: http://pubs.acs.org/doi/suppl/10.1021/np000114o-
dc.description.abstractThree eremophilanolides, 1α-acetoxy-8β-methoxy-10βH-eremophil-7(11)-en-8α,12-olide (1); 1α-angeloyloxy-6β-hydroxy-8β-methoxy-10βH-eremophil-7(11)-en-8α,12-olide (2); and 1α-angeloyloxy-8βH,10βH-eremophil-7(11)-en-8α,12-olide (3), and two pyrrolizidine alkaloids, integerrimine (4) and its N-oxide (5), were isolated from bioactive fractions of Senecio miser. The structures of the new compounds 1 and 2 were established by NMR spectroscopic analysis and chemical transformation. The X-ray analysis of compound 1 was also performed. Eremophilanolides 1 and 2 and alkaloids 4 and 5 were found to be strong insect antifeedants, further supporting a proposed defensive role for these classes of compounds.-
dc.description.sponsorshipThis work has been partially supported by a grant from the Consejería de Educación, Cultura y Deportes, Government of Canary Islands (1999/076), DGICYT-Spain (PB97-1226), DICYT-Chile (USACH), and a Collaborative Research Grant from CSIC-USACH.-
dc.format.extent2373 bytes-
dc.format.extent92882 bytes-
dc.format.mimetypetext/plain-
dc.format.mimetypeapplication/pdf-
dc.language.isoengen_US
dc.publisherAmerican Chemical Society-
dc.publisherAmerican Society of Pharmacognosy-
dc.rightsclosedAccessen_US
dc.titleDefensive chemistry of Senecio miseren_US
dc.typeartículoen_US
dc.identifier.doihttp://dx.doi.org/10.1021/np000114o-
dc.relation.publisherversionhttp://dx.doi.org/10.1021/np000114o-
dc.contributor.funderDirección General de Investigación Científica y Técnica, DGICT (España)-
dc.contributor.funderGobierno de Canarias-
dc.contributor.funderConsejo Superior de Investigaciones Científicas (España)-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003339es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100008737es_ES
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