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dc.contributor.authorMazoir, Noureddineen_US
dc.contributor.authorBenharref, Ahmeden_US
dc.contributor.authorBailén, Maríaen_US
dc.contributor.authorReina, Matías-
dc.contributor.authorGonzález-Coloma, Azucena-
dc.date.accessioned2009-04-28T07:15:45Z-
dc.date.available2009-04-28T07:15:45Z-
dc.date.issued2008-03-04en_US
dc.identifier.citationPhytochemistry 69(6): 1328-1338 (2008)en_US
dc.identifier.issn0031-9422-
dc.identifier.urihttp://hdl.handle.net/10261/12612-
dc.description11 pages, 1 figure, 1 table, 2 schemes.-- PMID: 18304594 [PubMed].-- Printed version published Apr 2008.-
dc.description.abstractWe have investigated the antifeedant and toxic effects of 23 semisynthetic terpenoid derivatives obtained through chemical modifications of the major components of Euphorbia resinifera (α-euphol and α-euphorbol) and E. officinarum (obtusifoliol and 31-norlanostenol) latex on several insect species (Spodoptera littoralis, Myzus persicae and Rhopalosiphum padi), their selective cytotoxicity on insect Sf9 and mammalian CHO cells and their phytotoxic effects on Lactuca sativa. The conversions focused mainly on positions 3, 7, 11, and 24 with several oxidizing agents. A total of 18 compounds affected S. littoralis growth (IGR). Our results support the importance of the C-3 substituent, suggest the involvement of the C-7 substituent and indicate that the C-3 hydroxyl is not essential for the IGR effect. Overall, Sf9 cells were more sensitive to the active compounds than CHO cells. All of these compounds had non selective moderate phytotoxic effects on radicle elongation of L. sativa.-
dc.description.sponsorshipThis work was supported by Grants Nos. CTQ2006-15597-C02-01/PPQ, CSIC-CNRST (2004MA0009/2005MA0003) and M. Bailén by a predoctoral I3P-CSIC fellowship.-
dc.format.extent2373 bytes-
dc.format.extent680148 bytes-
dc.format.mimetypetext/plain-
dc.format.mimetypeapplication/pdf-
dc.language.isoengen_US
dc.publisherElsevier-
dc.rightsclosedAccessen_US
dc.subjectEuphorbia-
dc.subjectTriterpene-
dc.subjectInsect growth regulation-
dc.subjectSpodoptera littoralis-
dc.titleBioactive triterpene derivatives from latex of two Euphorbia speciesen_US
dc.typeArtículoen_US
dc.identifier.doi10.1016/j.phytochem.2008.01.004-
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.phytochem.2008.01.004-
dc.contributor.funderEuropean Commission-
dc.contributor.funderConsejo Superior de Investigaciones Científicas (España)-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000780es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003339es_ES
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