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Título

Antimicrobial activity of Dunaliella salina sub and supercritical CO2 extracts

AutorMendiola León, Jose Antonio ; Santoyo, Susana ; Cifuentes, Alejandro ; Reglero, Guillermo ; Ibáñez, Elena
Palabras claveDunaliella salina
Supercritical fluid extraction
GC-MS
Antimicrobial
Fecha de publicaciónjun-2008
EditorInternational Association for Food Protection
SerieVol. 71
Issue 10
ResumenOn the search of new antimicrobial agents useful for the food industry, the activity of carbon dioxide extracts of Dunaliella salina has been tested against several microorganisms (Escherichia coli, Staphylococcus aureus, Candida albicans and Aspergillus niger). To be able to test extracts with very diverse chemical composition, a wide range of extraction conditions have been used considering both, the liquid and the supercritical region; extraction pressures ranged from 182 to 437 atm and extraction temperatures from 9.8 to 45.2 ºC. The extracts were analyzed by GC-MS in order to identify the compounds responsible of the antimicrobial activity detected: 14 different volatile compounds as well as several fatty acids were identified. The highest antimicrobial activity was obtained using 310 atm and 9,8 ºC; in these conditions, the presence of an indolic derivative was detected in the extract which has never been reported in Dunaliella salina, together with polyunsaturated fatty acids and compounds related to carotene metabolism, such as, β-ionone, neophytadiene, with known antimicrobial activity.
Versión del editorhttp://www.ingentaconnect.com/content/iafp/jfp/2008/00000071/00000010/art00031?token=00481e56a9f2f87b5e5fb55c5f3b3b47675448783b247b6e4a467b6c4f58762f6799ae3e
URIhttp://hdl.handle.net/10261/12528
ISSN0362-028X
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