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dc.contributor.authorVázquez, José Antonioes_ES
dc.contributor.authorPastrana, Lorenzoes_ES
dc.contributor.authorPiñeiro, Carmenes_ES
dc.contributor.authorTeixeira, José A.es_ES
dc.contributor.authorPérez Martín, Ricardo Isaaces_ES
dc.contributor.authorRodríguez-Amado, I.es_ES
dc.identifier.citationMarine Drugs 13(10): 6537-6549 (2015)es_ES
dc.description13 páginas, 3 figuras, 2 tablas.-- This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citedes_ES
dc.description.abstractThis work investigates the production of hyaluronic acid (H) by Streptococcus equi subsp. zooepidemicus in complex media formulated with peptones obtained from Scyliorhinus canicula viscera by-products. Initially, in batch cultures, the greatest productions were achieved using commercial media (3.03 g/L) followed by peptones from alcalase hydrolyzed viscera (2.32 g/L) and peptones from non-hydrolyzed viscera (2.26 g/L). An increase of between 12% and 15% was found in subsequent fed-batch cultures performed on waste peptones. Such organic nitrogen sources were shown to be an excellent low-cost substrate for microbial H, saving more than 50% of the nutrient costses_ES
dc.description.sponsorshipIsabel Rodríguez Amado was awarded with a postdoctoral contract from the Xunta de Galicia (Plan I2C, 2012). This research was funded by the projects MARMED 2011-1/164 (Atlantic Area Programme, EU), 0687_NOVOMAR_1_P (POCTEP Programme, EU) and iSEAS LIFE13 ENV/ES/000131 (LIFE+ Programme, EU). We acknowledge support by the CSIC Open Access Publication Initiative through its Unit of Information Resources for Research (URICI)es_ES
dc.publisherMultidisciplinary Digital Publishing Institutees_ES
dc.relation.isversionofPublisher's versiones_ES
dc.subjectViscera waste valorizationes_ES
dc.subjectHyaluronic acid productiones_ES
dc.subjectStreptococcus zooepidemicuses_ES
dc.subjectMarine peptoneses_ES
dc.subjectScyliorhinus canicula by-productses_ES
dc.subjectLogistic equationes_ES
dc.titleProduction of hyaluronic acid by Streptococcus zooepidemicus on protein substrates obtained from Scyliorhinus canicula discardses_ES
dc.description.peerreviewedPeer reviewedes_ES
dc.contributor.funderConsejo Superior de Investigaciones Científicas (España)-
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