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Production of hyaluronic acid by Streptococcus zooepidemicus on protein substrates obtained from Scyliorhinus canicula discards

AuthorsVázquez, José Antonio ; Pastrana, Lorenzo ; Piñeiro, Carmen ; Teixeira, José A.; Pérez Martín, Ricardo Isaac ; Rodríguez-Amado, I.
KeywordsViscera waste valorization
Hyaluronic acid production
Streptococcus zooepidemicus
Marine peptones
Scyliorhinus canicula by-products
Logistic equation
Issue Date2015
PublisherMultidisciplinary Digital Publishing Institute
CitationMarine Drugs 13(10): 6537-6549 (2015)
AbstractThis work investigates the production of hyaluronic acid (H) by Streptococcus equi subsp. zooepidemicus in complex media formulated with peptones obtained from Scyliorhinus canicula viscera by-products. Initially, in batch cultures, the greatest productions were achieved using commercial media (3.03 g/L) followed by peptones from alcalase hydrolyzed viscera (2.32 g/L) and peptones from non-hydrolyzed viscera (2.26 g/L). An increase of between 12% and 15% was found in subsequent fed-batch cultures performed on waste peptones. Such organic nitrogen sources were shown to be an excellent low-cost substrate for microbial H, saving more than 50% of the nutrient costs
Description13 páginas, 3 figuras, 2 tablas.-- This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Publisher version (URL)http://dx.doi.org/10.3390/md13106537
Appears in Collections:(IIM) Artículos
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