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Título

A flexible method for the fabrication of gold nanostructures using oligonucleotide derivatives

AutorAviñó, Anna CSIC ORCID; Eritja Casadellà, Ramón CSIC ORCID ; Fitzmaurice, Donald J.; García de la Torre, Beatriz CSIC ORCID; Ongaro, Andrea; Stanca, Sarmiza Elena; DiSalvo, Andrea; Maninng, Brendan; Iacopino, Daniela
Palabras claveDNA nanobiotechnology
Gold nanoparticles
Self-assembly
Oligonucleotides
DNA
Fecha de publicaciónoct-2007
EditorTaylor & Francis
CitaciónNucleosides, Nucleotides and Nucleic Acids
ResumenSeveral linear and branched DNA structures from 80-200 nm with a biotine molecule in the middle have been prepared. These structures have been decorated by addition of positively charged gold nanoparticles carrying 4-(dimethylamino)pyridine ligands. Streptavidin binds to the central biotine molecule introducing a 20 nm gap in the structure in which a biotinylated nanoparticle can be introduced. The simplest structure (80 nm, linear) is formed by 4 oligonucleotides. By changing some of these components changes on length, shape, and recognition system easily can be introduced.
Versión del editorDOI: 10.1080/15257770701548675
URIhttp://hdl.handle.net/10261/124965
DOI10.1080/15257770701548675
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