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Nanotechnology: Carbon nanotubes with DNA recognition

AuthorsWilliams, Keith A.; Veenhuizen, Peter Th M; García De La Torre, Beatriz; Dekker, C.; Eritja Casadellà, Ramón
molecular recognition
Issue Date26-Dec-2002
PublisherNature Publishing Group
AbstractSince the discovery of their one-dimensional electronic band structure1, the leading candidate that has emerged for nanodevice applications is single-walled carbon nanotubes (SWNTs) . Here we unite their unique properties with the specific molecular-recognition features of DNA by coupling SWNTs to peptide nucleic acid (PNA, an uncharged DNA analogue2) and hybridizing these macromolecular wires with complementary DNA. Our findings provide a new, versatile means of incorporating SWNTs into larger electronic devices by recognition-based assembly, and of using SWNTs as probes in biological systems by sequence-specific attachment.
Publisher version (URL)DOI: 10.1038/420761a
Appears in Collections:(IQAC) Artículos
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