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http://hdl.handle.net/10261/124664
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Martínez-Balbás, Marian | es_ES |
dc.date.accessioned | 2015-11-09T09:31:00Z | - |
dc.date.available | 2015-11-09T09:31:00Z | - |
dc.date.issued | 1994-02-25 | - |
dc.identifier.citation | Gene 139(2): 211-214 (1994) | es_ES |
dc.identifier.issn | 0378-1119 | - |
dc.identifier.uri | http://hdl.handle.net/10261/124664 | - |
dc.description.abstract | The simian virus 40 (SV40) enhancer contains three 8-bp purine-pyrimidine (R:Y) alternating sequences (Z-motifs) which are known to adopt the left-handed Z-DNA conformation in vitro. Mutations at these three Z-motifs seriously impair enhancer function. Reversion of one of these mutants (dpm12) is studied in this paper. The results indicate that, depending on growth conditions, recovery of the enhancer function is achieved through different mechanisms. Mutant viruses growing in solid-agar medium do not revert. On the other hand, revertants obtained in liquid medium contain a duplication of the enhancer sequences, showing no recovery of the original Z-motifs. © 1994 | es_ES |
dc.description.sponsorship | This work was financed by grants from the Comision Interministerial de Ciencia y Tecnologia (BI088-0236) the Commisio Interderpartamental de Recerca i Innovacio Tecnologica (89/4700) and the Commission of the European Communities [ ST2J-0372-C( A) and BAP-0466.E( JR)] | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | closedAccess | es_ES |
dc.subject | Culture medium | es_ES |
dc.subject | Homologous recombination | es_ES |
dc.subject | Recombinant selection | es_ES |
dc.subject | Z-motif | es_ES |
dc.title | Reversion of a simian virus 40 enhancer mutant depends on the growth conditions | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1016/0378-1119(94)90757-9 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1016/0378-1119(94)90757-9 | es_ES |
dc.contributor.funder | Comisión Interministerial de Ciencia y Tecnología, CICYT (España) | es_ES |
dc.contributor.funder | Generalitat de Catalunya | es_ES |
dc.contributor.funder | European Commission | es_ES |
dc.relation.csic | Sí | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100007273 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100002809 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | artículo | - |
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accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
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